Point of care influenza A+B test

Unique point-of-care test for Influenza A+B. Easy and fast diagnosis with nasal of pharyngeal swab.

The Capilia™ Flu Neo test will give you a positive or negative result from nasal or pharyngeal swab in 8 minutes. The swab medium can also be used for other Capilia™ tests, such as RSV, hMPV and Adeno. No special instruments or equipment are required.

 

Because the Influenza virus is highly contagious, rapid diagnosis and prompt treatment can have a positive effect on public health. Also, the ability to distinguish between A or B can help physicians to prescribe an appropriate antiviral therapy.

Type A Sensitivity/Specificity: 94,3%/95,4% (From nasal swabs)

Type B Sensitivity/Specificity: 100%/98,7% (From nasal swabs)

 

The Capilia™ Flu Neo, as shown above, is based on an immunochromatography assay using a monoclonal antibody that recognizes influenza virus antigens. When a nasal or pharyngeal swab is taken, the swab medium is applied to the sample area. Result will follow in 8 minutes.

Point-of-care tests from Tauns laboratories

These unique products offer point-of-care diagnostics in minutes for laboratories and general practitioners, using only nasal and pharyngeal swabs as samples.

 

The Capilia™ product line by Tauns laboratories offers fast and sensitive POCT detection of pathogens like Influenza, RSV or hMPV.

Easy-to-use point of care strips, as shown below in the Flu Neo test.

 

  • Rapid test for detecting antigen: Permitting accurate results; simple and easy to use
  • Easy to read Black Line: Adopting the latest nanotechnology,”Platinum-Gold Colloid”
  • Fast test results: Reading time is 3-8 min.
  • Shared use of extraction buffer in Capilia series:  1 sample can be used for 4 types of tests(Flu,Adeno,RSV,hMPV)

 

Other Capilia™ products include Mycoplasma, TB and Strep A.

 

New iNtRON Brochure on Real-time PCR products


RealMOD™ green SF series

A 2x Master Mix type including DNA interchelator SFC green dye and able to run Real-time PCR(qPCR) easily.

-Control Real-time PCR reaction volume
-Brighter fluorescence & long half-life
-SFC green : Similar wavelength compared to Eva green, SYBR Green
-Very stable and reproducible
-Hot-start function minimizing non-specific reaction

RealMOD™ green W² series
A SYBR green type and able to run Real-time(qPCR) easily

-High specificity and reproducibility
-High efficiency to detect low copy target
-Improvement of signal-to-noise due to high sensitivity
-Excellent results of qPCR even with template containing high GC contents

RealMOD™ AP / HP
Run Real-time PCR regardless of presence of ROX dye

-High specificity and reproducibility
-High efficiency to detect low copy target
-Signal-to-noise is rare due to high sensitivity
-Excellent result even containing high GC contents and long template (up to 500bp)

 

Intron Brochure

Molzym developments in molecular diagnostics

Product Highlights:

·         Micro-Dx™

Fast and precise culture-independent diagnosis of body fluids and tissues by innovative automated pathogen DNA extraction and broad-range 16S/18S rRNA gene PCR and sequencing.

·         SepsiTest™-UMD

Culture-independent routine diagnosis of bacteria and fungi from clinical samples including manual pathogen enrichment and DNA extraction combined with broad-range molecular analysis.

Micro-Dx™

Fast and precise culture-independent diagnosis of body fluids and tissues by innovative automated pathogen DNA extraction and broad-range 16S/18S rRNA gene PCR and sequencing.

Key features:

·      To be used with SelectNA™plus robot for microbial DNA extraction

·      Culture-independent detection of bacterial and fungal DNA

·      Sanger sequencing identification of typical and rare species from more than 300 eubacterial and 65 panfungal genera

·      Validated for: whole blood, BAL, aspirates of ascites, CSF and joints, urine, platelet concentrates, heart valves, abscesses, swabs

·      CE IVD marked

 >>Product Flyer

 

SepsiTest™-UMD

Culture-independent routine diagnosis of bacteria and fungi from clinical samples including manual pathogen enrichment and DNA extraction combined with broad-range molecular analysis.

Key features:

·      Microbial DNA extraction and 16S/18S rRNA gene PCR assays

·      Validated for various clinical specimens: body fluids up to 10ml, tissues and swabs

·      Identification of non-growing pathogens during antibiotic treatment

·      Precise identification of both typical and rare pathogens, including anaerobic and fastidious organisms by Sanger sequencing

·      CE IVD marked

>>Product Flyer

Lactose intolerance PCR test (LCT 13910C>T)

The patient friendly solution to lactose intolerance testing

The Lactose intolerance is usually tested with a drink containing lactose. After two hours a blood sample will be taken to measure how much glucose is in the blood. If the blood glucose level does not rise, this means that the body is not digesting or absorbing lactose. This way of analyzing the lactose tolerance is very patient unfriendly.

A better solution would be to just take blood sample and run a molecular test. ViennaLab offers a LCT RealFast Assay. This PCR test tests on the LCT 13910C>T mutation.

Unique features of the RealFast Assays

The RealFast Assays from ViennaLab are a great product line. All RealFast assays can be combined in the same thermocylcer. This because the thermocycling program is identical for all RealFast Assays. this way the Lactose intolerance test can be combined with tests like HFE, FV and FII(PTH).

HLA-B27 PCR Test

HLA-B27 is a genetic risk factor for seronegative spondyloarthropathies, such as ankylosing spondylitis, reactive arthritis, juvenile rheumatoid arthritis and anterior uveitis.

The HLA-B27 PCR test from Viennalab is known for its high quality but especially for its exceptional speed. The very short PCR program ensures that the results are generated quickly and accurately. All Viennalab PCR tests can also be carried out with the same protocol. This means you do not have to save up your samples from various genetic analysis.  With the RealFast assays you can combine analysis like Haemachromatosis, Factor V leiden, PTH & HLA B27 in one PCR run.

Furthermore, the HLA-B27 PCR test can be combined with a verified fast and low priced DNA isolation kit, which means that the total costs can be kept interesting. More…

 

A new PCR-system to run a quick qPCR in 15 minutes?

quick qPCRYes! And it is coming to the BeNeLux!

The PCRmax Exo 48 utilises a patented block and an optical technologie to deliver extreme speed, sensitivity and data quality. Optimised protocols will run a quick qPCR in as fast as 15 minutes. This all while using standard plasticware and consumables.

But why “Eco”

A unique 48-well polypropylene PCR plate utilising the same geometry as standard 384-well plates, but only 1/8 of the size. This enables users to dramatically reduce the qPCR reagent volumes compared to traditional 96-well instruments, whilst still producing a strong fluorescence signal. Minimizing the plate size also significantly improves thermal uniformity. A minimum volume of 5µl is validated, cutting reagent costs in half and making more efficient use of expensive and hard to acquire template DNA samples. More…

Would you like to see how this quick qPCR system works?

Here is a video on the PCRmax ECO48 Real-time qPCR system.

Request a Free PCRmax Demo

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16S-23S Comparison SelectNa Plus, Qia-amp and Purelink

The implementation of 16S-23S Next Generation Sequencing (NGS) for the detection of pathogens in clinical samples is an emerging area in clinical diagnostics. Certe and the UMCG have developed a novel, culture independent, method that detects and identifies bacterial species directly from clinical samples by targeted NGS of the 16S-23S rDNA region.

A barrier is the ratio of eukaryote to pathogen DNA isolated from samples with a low pathogen load. DNA extraction methods that feature selective lysis of eukaryote cells and subsequent degradation of the released eukaryote DNA followed by isolation of purified microbial DNA could improve the sensitivity of 16S-23S rDNA NGS.

We compared the MolYsis SelectNA plus DNA extraction kit (Molzym) and QIAamp DNA Microbiome DNA extraction kit (Qiagen), both featuring eukaryote DNA depletion, with the Purelink Genomic DNA mini kit (Invitrogen) which extracts total DNA, for sensitivity and depletion of eukaryote DNA using 16S-23S rDNA NGS.

Please click below for the full article.

Comparison_MolYsis_SelectNA Plus

 

Comprehensive CE-IVD CYP2D6 assay

The cytochrome P450 2D6 (CYP2D6 assay) is an important liver enzyme involved in the metabolism of up to 25% of clinically used drugs (e.g. tamoxifen, opiates, anti-depressives or anti-psychotics). The CYP2D6 gene is highly polymorphic with over 100 allelic variants and numerous sub-variants described in the Human Cytochrom P450 Database (www.cypalleles.ki.se).

Request a FREE CYP2D6 kit!

While the most frequent allelic variations are caused by single nucleotide polymorphisms (SNPs) and small insertions or deletions, highly homologous regions in the CYP2D6 gene locus facilitate unequal cross-over leading to large deletions, duplications and gene conversions. Most of these alterations result in a change of the CYP2D6 enzyme activity. Guidelines recommend to determine the CYP2D6 genotype of patients prior to medication in order to be able to estimate the metabolic activity of the enzyme, and in consequence the clinical efficacy or even the applicability of defined drugs.

Please click below for the full article.

Comprehensive analysis of CYP2D6 variants and copy numbers using reverse-hybridization and real-time PCR based assays

Rapid detection Candida albicans and fungal pathogens in blood

Arcis BiotechnologyCandida albicans species are common human commensals that can cause disseminated infection.
In fact, Candidaalbicans (the major cause of invasive candidiasis), has become one of the pathogens most frequently isolated from the blood of postoperative and immunocompromised patients during the last decade.

However, diagnosis remains difficult and tests have been developed to detect circulating Candida antigens for rapid diagnosis of disseminated candidiasis, but no PCR-based test has set the standard for molecular detection yet. In this work, a rapid system for blood processing is described that allows extraction and stabilisation of all fungal genomic targets.

This novel technology has produced a proof of concept by teaming up with a new specific and sensitive qPCR test for the timely and accurate diagnosis Candida and concomitant fungal infections. A finer analysis within a small cohort of clinical specimens has allowed to set a basic LOD on par with blood culture, requiring a total time of 3 hours to complete the entire process (extraction and detection).

Click below for the full article.

A novel processing technology for simple and rapid detection of Candida albicansand fungal pathogens in blood by qPCR

Request a free DNA Pathogen extraction kit