StripAssay® cah pcr
• Congenital adrenal hyperplasia (CAH) is an inherited disorder of steroid hormone synthesis
• Severe forms of CAH cause life-threatening salt-wasting crisis and virilization in newborns
• Appropriate treatment demands early diagnosis
• Hormone testing has a high false positive rate
The ViennaLab CAH StripAssays®
• are based on reverse-hybridization of biotinylated PCR products
• combine probes for mutations and controls in a parallel array of allele-specific oligonucleotides
• work with immobilized oligos on a teststrip
• show mutations by enzymatic color reaction easily visible to the naked eye
Application Note: Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia
| Product | Cat. | Capacity | Application |
|---|---|---|---|
| CAH StripAssay® | 4-380 | 20 Tests | Testing for 11 CYP21A2 mutations |