Dermatophytes test EuroBio

New CE-IVD Dermatophytes PCR test

We would like to introduce to you our newest assay:
The Dermatophytes test from EuroBio Scientific. The Dermatophytes test is a Real-Time PCR kit and is designed for the qualitative detection of the 6 most frequently involved dermatophytes in superficial cutaneous mycosis of the skin, hair and nails which are:
     – Trichophyton rubrum/violaceum (undifferentiated detection of these two species)
     – Trichophyton mentagrophyte var. interdigitale
     – Trichophyton tonsurans
     – Microsporum canis
     – Epidermophyton floccosum

Extracted DNA is the starting material for the Dermatophytes test and has been validated on pure cultures of dermatophytes fungi isolated from clinical samples and on mycological clinical samples (swabs rubbed on the scalp, nails, skin, hair and dander). The extraction from samples is done in two wells/tubes using two reactions. The DNA extraction and PCR inhibition control allows to check for variations that may have occured during the DNA extraction step of biological samples and the Real-Time PCR.

If you want to know more about this product, click on the button below to open the manual.

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Copyright © 2020 Goffin Molecular Technologies

Accurate detection of Alpha-1 antitrypsin deficiency

Accurate detection of Alpha-1 antitrypsin deficiency

Alpha-1 antitrypsin deficiency (AAT deficiency) is a common hereditary disorder in persons of northern European heritage. AAT is a protein that is mainly produced in the liver, it inactivates proteases like neutrophil elastase in the lungs in healthy persons. If a person has an AAT deficiency, the proteins don’t have the right shape and get stuck in the liver cells. This will cause, among other things, shortness of breath, lung infections and tiredness. People with AAT deficiency usually develop the first sings between ages 20 and 50. About 10% of infants with AAT deficiency develop liver disease.

Individuals carrying the PI*ZZ genotype have a higher risk of developing emphysema and liver disease. PI*SZ carriers have lower risk and PI*MM, *MS or *SS genotypes have normal or slightly decreased AAT plasma levels.

The AAT RealFast™ Assay is a real-time PCR that detects the PI*S and PI*Z variants of the SERPINA1 gene. In a human DNA extract, the assay discriminates all of the possible genotypes: PI*MM, PI*MS, PI*MZ, PI*SZ and PI*SS or PI*ZZ.

Goffin Molecular Technologies offers this test as well as other tests for genetic disorders, for more information click here.

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Additional study for saliva samples and COVID-19

Additional study for saliva samples and COVID-19

Last week we published a post regarding a COVID-19 determination by using saliva samples instead of nasopharyngeal swabs. You can find this post by clicking here. In this post we proved that saliva samples give the same results for COVID-19 determination as nasopharyngealswabs. This can be seen in the publication by clicking on the button below that page.

This time we want to take it a step further, and prove to you that saliva samples work even better. Because you can not only detect viral RNA with saliva samples just like nasopharyngeal swabs, but immunoglobulins too. Because of this, you don’t have to do a bloodtest making saliva superior once again. By sampling saliva from persons that need to be tested for viral RNA and/or antibodies, both of these determinations can be done at will. By clicking on the button below, you can read the publication that proves this.

If you are interested in validating these saliva collectors yourself, please contact us by clicking here.

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Tired of thawing with hands

Tired of thawing with hand?

Are you tired of thawing cell preparation test tubes by hand? We can now present you the DYNAThaw. The thawing process is standardized and can be used in consulting rooms or laboratories. It’s able to pre-save thawing programs to save even more time. 

The typical thawing time is ca 3-4 min and the DYNAThaw uses a consistent temperature control for the highest safety of the samples.

For more information about the DYNAThaw click here.

Dynathaw
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StripAssay als vervanger voor RFLP

De StripAssay als vervanger voor RFLP

In Nederland wordt er vaak gebruik gemaakt van Restriction fragment length polymorphism (RFLP) om bekende mutaties aan te tonen. Hierbij knippen restrictie-enzymen het DNA op de plek van de mutaties, en worden de mutaties aangetoond met behulp van een gel. Maar bij deze techniek moeten gelen worden gemaakt en dit is erg arbeidsintensief en het automatiseren van deze techniek kost veel geld. Met deze techniek kan er voor alpha globuline op negen mutaties worden getest in tegenstelling tot de alpha globuline StripAssay van ViennaLab die 21 mutaties kan detecteren.

Deze StripAssay van ViennaLab dekken met 21 mutaties meer dan >90% van alle alpha globuline mutaties. De mutaties kunnen getest worden op twee aparte strips die alle mutaties bevatten.

Voor meer informatie over de α-Globin StripAssay® kan gevonden worden in de brochure en de handleiding.

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StripAssay as a substitute for RFLP

StripAssay as a substitute for RFLP

Restriction fragment length polymorphism (RFLP) is in the Netherlands a technique that is often used to detect mutations. With this technique restriction enzymes cut the DNA at the site of the mutations, and the mutations are identified using a gel. But with this technique gels have to be made which is very labor intensive and automating this technique costs a lot of money. But this technique allows testing of nine mutations for alpha globulin as opposed to the ViennaLab alpha globulin StripAssay which can detect 21 mutations.

The ViennaLab StripAssay covers with 21 mutations over >90% of all alpha globin mutations. The mutations can be tested of two separate strips that contain all the mutations.

More information about the α-Globin StripAssay® can be found in the brochure and the manual.

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