Chlamydia trachomatis PCR kit

Detection of chlamydia trachomatis by PCR

Chlamydia trachomatis is a bacteria that causes a sexually transmitted disease. The bacteria settles in the mucous membrames of the genitals, causing infections of the urethra, anus and in women the cervix. In men this bacteria can lead to epididymis or inflammation of the prostate. In women, this bacteria can lead to fallopian tube inflammation that can spread to the abdominal cavity, leading to pelvic inflamattory disease. Untreated infections can lead to infertility in women.

The incubation time of Chlamydia trachomatis takes 1 to 3 weeks, the disease is most common in women between 15 and 29 years and in men betweein 20 and 40 years. Chlamydio trachomatis has several serotypes. Serotypes D to K cause urogenital infections and conjunctivitis, which means that these serotypes initially do not cause any symptoms but can lead to infertility in the long term. Serotypes A, B and C cause trachoma in which the cornea is damaged, which can lead to blindness Finally, the serotypes L1, L2 and L3 cause lymphogranuloma venereum, which causes an infection in the lymph node, mainly due to anal intercourse.

Chlamydia trachomatis can be diagnosed by directly detecting the chlamydia specific nucleic acid by PCR in genital swabs, urine or eye swabs. One of the advantages of this kit is the fact it is secured by targeting the multicopy sequence of the 16s rRNA and it has dual target detection of the 16S rRNA gene and a cryptic plasmid. For this kit additional PCR reagents pipetting is not necessery. It has also a function of reliable detection of swedish variant of chlamydia caused by detecting a sequence variation in the cryptic plasmid.

PRODUCT ADVANTAGES

HIGH SENSITIVITY
Secured by targeting the multicopy sequence of the 16S rRNA gene and dual target detection of the 16S rRNA gene and a cryptic plasmid
SIMPLE LABORATORY WORKFLOW
Easily combinable with other PCR kits from the STI Panel in one workflow
EASY TO USE CONCEPT
Single tube Ready-To-Use Master Mix contains all component for PCR amplification and no additional PCR reagents pipetting necessary
RELIABLE DETECTION OF SWEDISH VARIANT OF CHLAMYDIA TRACHOMATIS
Elimination of false-negative results caused by a sequence variation in the cryptic plasmid
CONTAMINATION PREVENTION
Master Mix contains Uracil-DNA-Glycosylase and dUTP’s eliminating carryover contamination
COMPATIBLE WITH A WIDE RANGE OF REAL-TIME PCR DEVICES
CE IVD CERTIFIED DIAGNOSTIC TEST