The human parvovirus B19 belongs to the family Parvoviridae. In addition to human parvovirus B19, there are canine parvorvirus, feline panleucopenia virus and other parvoviruses that can cause disease in mammals and birds. Humans are not susceptible to infection with animal parvoviruses. The virus ends up in the epithelium of the future and travels through the bloodstream to the bone marrow. in 20 percent of people who become infected, the infection is asymptomatic. In a symptomatic infection of the parvovirus B19, it can cause a disease known as fifth disease. The fifth disease is a mild skin rash, which is especially harmful to children. Any other symptoms that are less common.

A week after infection, specific IgM and IgG are detectable. In this phase, symptoms such as exanthema and joint complaints occur, these symptoms can last for a few days to 2 weeks. During the acute infection, high concentrations of Parvovirus-B19 arise in the blood, which are easily detectable by PCR detection. This PCR detection can also be used to detect Parvovirus B19 in amniotic fluid and fetal blood.