HLA-A3101

The HLA system is a complex gene cluster encoding proteins vital for immune system functionality. Pharmacogenetics studies how genetic variations impact drug response, thereby aiding in the personalized treatment for various medical conditions. Within this context, HLA-A31:01 and HLA-B15:02 have been identified as risk factors for adverse drug reactions, notably cutaneous adverse reactions like Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).