Trichomonas vaginalis PCR kit

Immunoassay detection of the target sequence or beta-tubulin gene

Trichomonas vaginalis is a bacterium that lives parasiticly, in other words the bacterium needs a host to survive. Trichomonas can bind to the vaginal epithelium, when this happens the epithelium can become superficial to a host immune response. This reaction causes the greenish-yellow aspect of the secretion. Other symptoms that can occur in women are irritation and redness of the vaginal mucosa, and the smell of discharge also starts to smell. In men with an infection, hardly any attention is involved, men will generally clear the infection themselves after a few weeks.
A PCR test is recommended for detection of trichomonas vaginalis due to its overall higher specificity and sensitivity. This involves taking swabs from the cervix or urethra. The beta-tubulin gene serves as the target sequence during this diagnosis. This gene is responsible for the protein coding of trichomonas vaginalis. This protein forms a dimer with alpha-tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex with other brain malformations. Microtubules are rigid fibers that form the cytoskeleton, structural framework of the cell, also microtubules function as a track along which other proteins transport materials in cells, these are called motor proteins.

PRODUCT ADVANTAGES

  • HIGH SPECIFITY
    Secured by a multicopy sequence of hte beta-tubulin gene and ensures excellent sensitivity reaches up to 0,25cp/ ul. 
  • RELIABLE DETECTION
    Simple sensitive detection compared to wet mount microscopy and culture
  • EASY-TO-USE CONCEPT
    Single tube Ready-to-Use Master Mix contains all components for PCR amplification and no additional PCR reagents pipetting necessary
  • CONTAMINATION PREVENTION
    Master Mix contains Uracil-DNA glycosylase (UNG) and dUTPs eliminating carryover contamination
  • SIMPLE LABORATORY WORKFLOW
    Easily combinable with other GeneProof PCR kits in one workflow
COMPATIBLE WITH A WIDE RANGE OF REAL-TIME PCR DEVICES
CE IVD CERTIFIED DIAGNOSTIC TEST

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