Ureaplasma belongs to the group of genital mycoplasma organisms, ureaplasma can cause a urethritis that is sexually transmitted. Ureaplasma is parasitic, meaning it needs a host, such as humans or animals, to survive. Infected persons do not have to suffer from complaints when ureplasma is in balance with other bacteria.
For the diagnosis of ureaplasma, swabs are used from urethra, vagina or cervix and in men first-void urine. the target sequence for ureaplasma is the ureD gene, which is a gene that codes for the accessory proteins. This gene is also necessary for the urease activity, it is resistant to EDTA and sodium citrate and this gene is sensitive to flurofamide. Due to the urease activity of the gene, it forms the main component of the cytoplasm and is composed of several 70 kilo-kilodelton polypeptides.