PGX-5FU StripAssay

5-Fluorouracil (5-FU) is widely andPGX-5FU StripAssay successfully used for the treatment of solid tumors. In some patients, however, an enzyme variant results in the need of therapy adjustment. The PGX-5FU StripAssay identifies the most common mutation with therapeutic relevance for 5-FU treatment.

The ViennaLab PGX-5FU StripAssays®
• are based on reverse-hybridization of biotinylated PCR products
• combine probes for mutations and controls in a parallel array of allele-specific oligonucleotides
• work with immobilized oligos on a teststrip
• show mutations by enzymatic color reaction easily visible to the naked eye

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