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Apo E

The Apo E (Apolipoprotein E) is a protein crucial for lipid metabolism and transport within the body. Variations in the Apo E gene can significantly affect cholesterol levels and the risk of developing cardiovascular diseases, including atherosclerosis. It is also closely associated with Alzheimer’s disease and cognitive decline. There are three main isoforms—ApoE2, ApoE3, and ApoE4—each with distinct implications for health. ApoE4 carriers, for instance, have a higher likelihood of developing Alzheimer’s and coronary artery disease. Understanding one’s Apo E genotype is valuable for both preventative measures and tailored treatment plans, offering a nuanced approach to managing various health concerns.