CYP2D6, a member of the cytochrome P450 superfamily, is one of the most important liver enzymes involved in the metabolism of xenobiotics in the body. Numerous drugs prescribed for the treatment of breast cancer (tamoxifen), cardiacdiseases(antiarrhythmics, beta-receptor blockers), psychiatric disorders (antipsychotics, antidepressants) or pain(opiates) are substrates for CYP2D6. CYP2D6 stripassay
The ViennaLab PGX-CYP2D6 StripAssay detects detects the most common variants with impaired enzyme activity. It detects the allelic variants CYP2D6*3 (2637delA), CYP2D6*4 (193 G>A) and CYP2D6*6 (1795delT).
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