Mycobacterium tuberculosis PCR Kit

Dual targeting prevents detection failures caused by occurrence of mutations

Mycobacterium tuberculosis is a bacterium that causes tuberculosis, a chronic infection usually of the lungs. Symptoms of tuberculosis may include fever, cough, and weight loss. Pulmonary tuberculosis can also develop in the long term when granulomas develop as a result of the infections in the respiratory tract. Grouped granulomas cause tubercles causing pulmonary tuberculosis.

A primary infection sometimes occurs without symptoms, any symptoms that may appear are general symptoms such as fever, fatigue, weight loss and night sweats. Also in a post-primary infection there are general symptoms that are not very typical, unless there is a clear localization in the foreground.

When detecting mycobaterium tuberculosis, a distinction is made between the active disease and the latent infection. Because mycobacterium tuberculosis can settle in several places on the body, several swabs are taken for testing. If the disease is active, a diagnosis is quickly made by means of PCR, which does not always happen with the latent infection or a preliminary investigation is required first.

PRODUCT ADVANTAGES

DUAL TARGET DETECTION
Dual targeting prevents detection failures caused by occurrence of mutations Secured by targeting the multi-copy sequence IS6110 and MPB64
HIGH SPECIFICITY
Detection of all species from Mycobacterium tuberculosis complex (M. tuberculosis, M. africanum, M. bovis, M. microti, M. canetti, M. caprae, M. orygis, M. mundi and vaccination strain Bacillus Calmmette-Guérin, BCG)
WIDE RANGE OF VALIDATED CLINICAL MATERIALS
Enables detection from a broad spectrum of respiratory and gastrointestinal samples Sputum, BAL, swab, urine, CSF, plasma, stool
EASY-TO-USE CONCEPT
Single tube Ready-to-Use Master Mix contains all components for PCR amplification No additional PCR reagents pipetting necessary Simplifies laboratory workflow
CONTAMINATION PREVENTION
Master Mix contains Uracil-DNA glycosylase (UNG) and dUTPs eliminating carryover contamination
COMPATIBLE WITH A WIDE RANGE OF REAL-TIME PCR DEVICES
CE IVD CERTIFIED DIAGNOSTIC TEST