CYP2C19

CYP2C19 is a gene that encodes an enzyme belonging to the cytochrome P450 family, which plays a crucial role in the metabolism of various drugs in the body. This enzyme is responsible for the breakdown and elimination of several medications, including antidepressants, proton pump inhibitors, and certain antiepileptic drugs.

Variations in the CYP2C19 gene can significantly affect how individuals respond to medications. These genetic variations can categorize people into different metabolizer types: poor, intermediate, extensive, or ultra-rapid metabolizers.