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The GI Pathogen Panel by Igenesis is a fully automated molecular diagnostic test for detecting 12 key gastrointestinal pathogens from stool or anal swab samples. Compatible with the Galaxy Neo, Lite, and Pro systems, it uses multiplex PCR and melting curve analysis to deliver fast, reliable results in a closed system. Each test runs in a sealed, single-use iCassette, minimizing contamination risk and simplifying workflow. The system performs automated nucleic acid extraction, amplification, and detection with minimal hands-on time. Targeting pathogens like Salmonella, Shigella, Campylobacter spp., and Clostridioides difficile, the panel is ideal for routine diagnostics, infection control, and outbreak surveillance in clinical microbiology and molecular diagnostics laboratories.
The Igenesis GI Pathogen Panel is a multiplex test that detects and differentiates 12 pathogens commonly associated with diarrheal syndromes:
Vibrio cholerae
Vibrio parahaemolyticus
Vibrio fluvialis
Salmonella spp.
Shigella spp.
Campylobacter jejuni
Campylobacter coli
Clostridioides difficile
Yersinia enterocolitica
Aeromonas hydrophila
Plesiomonas shigelloides
Cronobacter sakazakii
Each kit contains 12 test-ready iCassettes, lyophilized reagents, and control materials. Samples are introduced into the cassette, which is then processed automatically by the compatible Galaxy platform.
The pathogens targeted by this GI Pathogen Panel represent a broad clinical spectrum of infectious diarrhea:
Clostridioides difficile is a major cause of healthcare-associated diarrhea.
Campylobacter, Shigella, and Salmonella are common foodborne pathogens with global prevalence.
Yersinia enterocolitica and Aeromonas hydrophila are often underdiagnosed but clinically significant.
Cronobacter sakazakii and Plesiomonas shigelloides are particularly relevant in pediatric and immunocompromised cases.
By targeting both routine and emerging pathogens, the panel enables precise syndromic diagnosis.
The Diarrheal Syndrome 12-Pathogen Nucleic Acid Detection Kit is a PCR-based test developed by Igenesis. It combines ease-of-use with high analytical performance. The kit is optimized for Galaxy Neo, Lite, and Pro qPCR systems and includes:
12 iCassettes preloaded with extraction and amplification reagents
Positive and negative control tubes
Sterile deionized water and lyophilized primer-probe mixes
All components are batch-specific and non-interchangeable. The cassettes must remain sealed until sample addition and be used within 30 minutes once opened.
This GI Pathogen Panel applies multiplex PCR and melting curve analysis for pathogen differentiation:
Sample Loading: Stool or anal swab added to the sealed iCassette
Automated Processing: Galaxy system performs nucleic acid extraction and amplification
Melting Curve Detection: Unique Tm values allow discrimination of each target
Result Output: Automated software displays typing and qualatative analysis
This self-contained, automated workflow ensures high reproducibility and low contamination risk — ideal for routine high-throughput labs.
This panel supports a range of diagnostic and surveillance applications:
Clinical diagnostics for acute diarrheal illness in hospitals and outpatient settings
Infection control by identifying transmissible agents such as Shigella and C. difficile
Public health investigations during foodborne outbreaks or travel-related infections
Special populations, such as immunocompromised or pediatric patients with unexplained diarrhea
The combination of multiplex capacity, automation, and broad target coverage makes the GI Pathogen Panel a valuable tool for modern molecular laboratories.
IFU
For any missing information or if you require additional details, please do not hesitate to contact us.
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