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Haemochromatosis StripAssay B

Short description

Elevate your diagnostic capabilities with the Haemochromatosis StripAssay B by ViennaLab. This cutting-edge assay offers unparalleled precision in identifying common HFE mutations associated with hereditary haemochromatosis. Its streamlined design, combined with a visible enzymatic color reaction, ensures swift and accurate diagnostics. Targeting critical mutations such as H63D, S65C, and C282Y, this assay empowers clinicians to initiate timely therapeutic interventions. The comprehensive kit includes all essential components for efficient diagnostics. Choose Haemochromatosis StripAssay B for precise, professional early detection, enhancing patient care and clinical outcomes.

Product highlights

  • Accurate Mutation Detection
  • Streamlined Diagnostic Process
  • Visible Color Reaction
  • Timely Intervention
  • HFE Mutation Focus

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Haemochromatosis StripAssay B



Instructions for Use

Brochure StripAssays


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Specifications of the Haemochromatosis StripAssay B

Haemochromatosis StripAssay B – Your Key to Effective Hereditary Haemochromatosis Diagnosis

Unlocking the Potential of Early Detection


In the realm of medical diagnostics, precision and timeliness are paramount. The ability to detect genetic disorders swiftly and accurately can be life-changing for patients and clinicians alike. Hereditary haemochromatosis, a genetic disorder affecting iron metabolism, is no exception. Characterized by the gradual accumulation of iron in vital organs like the liver, heart, and pancreas, this condition poses serious health risks if left untreated. Complications range from liver cirrhosis to diabetes, arthritis, and cardiomyopathies, with the gravest consequence being premature death due to liver cancer or organ failure.

However, hope shines brightly on the horizon. Early diagnosis can transform the trajectory of hereditary haemochromatosis. It allows for a simple yet remarkably effective treatment known as therapeutic bleeding, affording those affected the opportunity to lead nearly normal lives. Enter the Haemochromatosis StripAssay B, a pioneering product developed by ViennaLab, designed to revolutionize the diagnosis of hereditary iron overload.

Understanding Hereditary Haemochromatosis

Before diving into the details of this remarkable diagnostic tool, let’s grasp the essence of hereditary haemochromatosis. This genetic disorder comes in two primary forms: classical (type 1) haemochromatosis and non-HFE related forms. The former is primarily caused by mutations in the HFE gene, whereas the latter, though less common, results from mutations in other genes related to iron metabolism, such as Transferrin Receptor 2 (TFR2) and Ferroportin (FPN1). These genes encode proteins critical in regulating the body’s iron stores. When they undergo mutations, iron can accumulate excessively in organs and tissues, disrupting their normal functions.

The Crucial Role of Early Diagnosis

The saying “prevention is better than cure” couldn’t be truer in the context of hereditary haemochromatosis. Detecting the condition in its early stages is nothing short of a game-changer. It enables prompt intervention through therapeutic bleeding, effectively reducing iron levels in the body. This translates into a significantly improved quality of life for individuals with hereditary haemochromatosis, as they can avoid the debilitating complications that come with untreated iron overload.

Introducing Haemochromatosis StripAssay B

The ViennaLab Haemochromatosis StripAssay B is a breakthrough diagnostic solution that targets the most prevalent mutations associated with hereditary iron overload. This innovative product simplifies and enhances the diagnostic process, making early identification more accessible and efficient than ever before. Here’s how it works:

  1. Reverse-Hybridization of Biotinylated PCR Products: The journey begins with the isolation of DNA and the subsequent amplification of specific regions using biotinylated primers.
  2. Parallel Array of Allele-Specific Oligonucleotides: The amplification products are then exposed to a test strip containing allele-specific oligonucleotide probes immobilized in parallel lines.
  3. Enzymatic Color Reaction: What sets the Haemochromatosis StripAssay B apart is its user-friendly design. It simplifies the process by employing a visible enzymatic color reaction, easily discernible to the naked eye, when bound biotinylated sequences are detected using streptavidin-alkaline phosphatase and color substrates.

Haemochromatosis StripAssay B: Target Mutations

This remarkable diagnostic tool specifically targets the three most common HFE mutations associated with classical haemochromatosis:

  1. H63D
  2. S65C
  3. C282Y

These mutations are central to the development of hereditary iron overload. Identifying them early allows for timely therapeutic intervention, significantly improving patient outcomes.


In the world of medical diagnostics, the Haemochromatosis StripAssay B by ViennaLab shines as a beacon of hope for individuals affected by hereditary haemochromatosis. By simplifying and streamlining the diagnostic process, it empowers clinicians and patients alike to take control of their health. Early diagnosis is the key to effective therapy, and this innovative product stands as a vital tool in achieving this goal. The Haemochromatosis StripAssay B is not just a diagnostic tool; it’s a catalyst for improved patient outcomes and an enabler of healthier lives. Unlock the potential of early detection with Haemochromatosis StripAssay B, your key to effective hereditary haemochromatosis diagnosis.

Components of the Haemochromatosis StripAssay B
  • Lysis Solution (50 ml)
  • GENXTRACTTM Resin (5 ml)
  • Amplification Mix (yellow cap, 500 µl)
  • Taq Dilution Buffer (transparent cap, 500 µl)
  • DNAT (blue cap, 1.5 ml)
  • Typing Trays (3)
  • Teststrips (20)
  • Hybridization Buffer (white cap, 25 ml)
  • Wash Solution A (white cap, 80 ml)
  • Conjugate Solution (25 ml)
  • Wash Solution B (80 ml)
  • Color Developer (25 ml)
  • CollectorTM Sheet (1)

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