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BRAF is a specific gene that encodes for a protein crucial to cellular growth regulation. Mutations in the BRAF gene are often implicated in various forms of cancer, including melanoma, colorectal cancer, and thyroid cancer. The most common BRAF mutation is BRAF V600E, which leads to an overactive BRAF kinase that promotes tumor growth. Identification of BRAF mutations is essential for targeted cancer therapies. Drugs like vemurafenib and dabrafenib specifically target BRAF mutations, offering a more focused treatment approach compared to traditional chemotherapy. Understanding the BRAF status is therefore pivotal for effective cancer management and personalized treatment plans.