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Liquid biopsy is a revolutionary technique in cancer diagnostics that uses a simple blood sample to detect cancer-related genetic mutations and alterations. This non-invasive method offers a snapshot of the tumor’s genetic landscape, allowing for early detection, monitoring response to treatment, and identifying possible resistance mechanisms. It provides a dynamic view of the cancer’s evolution, which can be crucial for adapting treatment strategies. Because it eliminates the need for invasive tissue biopsies, liquid biopsy is becoming an increasingly attractive option for both healthcare providers and patients.